Nuclear model calculation for cyclotron production of Cu-61 as a PET imaging

作者：Sadeghi Mahdi^*; Zandi Nadia; Bakhtiari Mahdi

来源：Journal of Radioanalytical and Nuclear Chemistry, 2012, 292(2): 777-783.

DOI：10.1007/s10967-011-1557-1

• Excitation function
• Cu-61
• Physical yield
• TALYS-1.2
• ALICE/ASH
• Ni electroplating

Cu-61 is positron emitter and can be used as the PET and molecular imaging. In this study cyclotron production of Cu-61 via Ni-61(p,n)Cu-61, Ni-nat(p,x)Cu-61, Ni-nat(d,x)Cu-61, Ni-nat(alpha,x)Cu-61, Zn-nat(p, x)Cu-61 and Co-59(alpha,2n)Cu-61 reactions was investigated. The ALICE/ASH (hybrid and GDH models) and TALYS-1.2 codes were used to calculate excitation functions for proton, alpha and deuteron induced on Ni-nat, proton on Ni-61 and Zn-nat and also alpha-particle on Co-59 targets that lead to the production of Cu-61 radioisotopes using intermediate energy accelerators. In addition, we compared the data obtained from in this study with the reported measurement by experimental data. Moreover, optimal thickness of the targets and physical yield were obtained by stopping and range of ions in matter code for each reaction. Eventually Ni-61(p,n)Cu-61 and Co-59(alpha,2n)Cu-61 reaction to produce Cu-61 in no-carrier added state with high production yield was suggested. Finally the Ni-nat(p,x)Cu-61 reaction was employed to test the target preparation using electroplating technique.

• 出版日期2012-5