Association analysis of polymorphism in KIAA1717, HUMMLC2B, DECR1 and FTO genes with meat quality traits of the Berkshire breed

作者：Lee Yong Hwa; Kwon Eun Jung; Cho Eun Seok; Park Da Hye; Kim Byeong Woo; Park Hwa Chun; Park Beom Young; Jang Ik Soon; Choi Jong Soon; Bang Woo Young^*; Kim Chul Wook

来源：African Journal of Biotechnology, 2011, 10(25): 5068-5074.

• Berkshire
• genetic markers
• meat quality
• SNP

Single nucleotide polymorphisms (SNPs) in KIAA1717, HUMMLC2B, DECR1, and FTO genes have been found to be associated with some pork meat quality traits. In this study, we discovered that, in addition to meat quality traits reported previously, SNPs in these genes also are significantly associated with other meat quality traits in the Berkshire breed. A total of 323 Berkshire pigs bred under the same conditions were used for meat quality evaluation and polymerase chain reaction-amplified genes with restriction endonucleases (PCR-RFLP) genotyping analyses. The association analysis of RFLP genotyping with meat quality traits revealed that the SNPs in these 4 genes have novel associations with multiple meat quality traits (p < 0.01 or p < 0.05); a SNP in KIAA1717 was associated with meat color (CIE L), backfat thickness, drip loss, water-holding capacity, and pH(24hr); a SNP in HUMMLC2B was associated with chemical composition (collagen), drip loss, shear force, and pH(24hr); a SNP in DECR1 was associated with meat color (CIE a and b) and backfat thickness; and a SNP in FTO was associated with meat color (CIE L, a and b), protein content, drip loss, and water-holding capacity. Taken collectively, our results suggest that these 4 SNPs may be used for marker-assisted selection as a genetic marker for meat quality traits in Berkshire pigs.

• 出版日期2011-6-8