A solid-phase affinity labeling method for target-selective isolation and modification of proteins

作者:Kuwahara Daichi; Hasumi Takahiro; Kaneko Hajime; Unno Madoka; Takahashi Daisuke*; Toshima Kazunobu
来源:Chemical Communications, 2014, 50(98): 15601-15604.
DOI:10.1039/c4cc06783e

摘要

Solid-phase affinity labeling of a target protein, peanut agglutinin (PNA), with the specifically designed chemical tool 1 selectively and effectively furnished the labeled PNA. Furthermore, this method was applicable to native human carbonic anhydrase II in red blood cell lysate using the chemical tool 2 without the need for tedious manipulations.

  • 出版日期2014