Aminomethylation of N-methylmorpholinium 6-amino-4-aryl-3,5-dicyano-1,4-dihydropyridine-2-selenolates as an approach to the preparation of 3,5,7,11-tetraazatricyclo[7.3.1.0(2,7)]tridec-2-ene-8-selenone derivatives

作者：Frolov K A^*; Dotsenko V V; Krivokolysko S G

来源：Russian Chemical Bulletin, 2013, 62(6): 1401-1404.

DOI：10.1007/s11172-013-0201-3

• N-methylmorpholinium 6-amino-4-aryl-3,5-dicyano-1,4-dihydropyridine-2-selenolate
• multicomponent cyclocondensation
• cyanoselenoacetamide
• Mannich reaction
• 3,5,7,11-tetraazatricyclo[7.3.1.0(2,7)]tridec-2-ene-8-selenone

A reaction of N-methylmorpholinium 6-amino-4-aryl-3,5-dicyano-1,4-dihydropyridine-2-selenolates with primary amines and excess of formaldehyde leads to 3,5,7,11-tetraazatricyclo[7.3.1.0(2,7)]tridec-2-ene-8-selenone derivatives. The same compounds were obtained by a multicomponent cascade cyclocondensation of benzaldehyde, cyanoselenoacetamide, primary amine, and excess of formaldehyde.

• 出版日期2013-6