Vitamin D and IBD: Can We Get Over the "Causation" Hump?

作者:Ananthakrishnan Ashwin N*
来源:American Journal of Gastroenterology, 2016, 111(5): 720-722.
DOI:10.1038/ajg.2016.47

摘要

Vitamin D deficiency is common in patients with inflammatory bowel diseases and may even precede the disease onset contributing to an increased risk. Using comprehensive data from a large, referral IBD cohort, Kabbani et al. establish that low vitamin D levels are associated with greater disease activity, increased risk of surgery and hospitalizations, and lower health-related quality of life in patients with IBD. This expands the evidence base supporting such an association. However, there is a need for this field to evolve to interventional studies with vitamin D supplementation to confirm that vitamin D has a true therapeutic role for treating disease activity in IBD.

  • 出版日期2016-5