Non-tuberculous Mycobacteriosis with T-cell Lymphoma in a Red Panda (Ailurus fulgens)

作者：Fuke N; Hirai T^*; Makimura N; Goto Y; Habibi W A; Ito S; Trang N T; Koshino K; Takeda M; Yamaguchi R

来源：Journal of Comparative Pathology, 2016, 155(2-3): 263-266.

DOI：10.1016/j.jcpa.2016.06.001

• Mycobacterium gastri
• non-tuberculous mycobacteriosis
• red panda
• T-cell lymphoma

A 9-year-old male red panda (Ailurus fulgens) became emaciated and died. Necropsy examination revealed systemic lymphadenomegaly. The liver, lungs and left kidney contained multifocal yellow nodules. Microscopical examination revealed granulomatous inflammation in the liver, lungs, kidney, spleen and lymph nodes, with numerous acid-fast bacilli. Sequencing of genetic material isolated from the tissues classified the pathogen as Mycobacterium gastri. Lymphoma was found in the liver, lungs, kidney and lymph nodes. The neoplastic cells were strongly labelled for expression of CD3, Ki67 and proliferating cell nuclear antigen by immunohistochemistry. This is the first report of M. gastri infection with T-cell lymphoma in a red panda.

• 出版日期2016-10