Natural Killer Cell Memory

作者:O' Sullivan Timothy E; Sun Joseph C; Lanier Lewis L
来源:Immunity, 2015, 43(4): 634-645.
DOI:10.1016/j.immuni.2015.09.013

摘要

Natural killer (NK) cells have historically been considered short-lived cytolytic cells that can rapidly respond against pathogens and tumors in an antigen-independent manner and then undergo cell death. Recently, however, NK cells have been shown to possess traits of adaptive immunity and can acquire immunological memory in a manner similar to that of T and B cells. In this review, we discuss evidence of NK cell memory and the mechanisms involved in the generation and survival of these innate lymphocytes.

  • 出版日期2015-10-20