Accurate quantification of magnetic particle properties by intra-pair magnetophoresis for nanobiotechnology

作者：van Reenen Alexander; Gao Yang; Bos Arjen H; de Jong Arthur M; Hulsen Martien A; den Toonder Jaap M J; Prins Menno W J^*

来源：Applied Physics Letters, 2013, 103(4): 043704.

DOI：10.1063/1.4816429

The application of magnetic particles in biomedical research and in-vitro diagnostics requires accurate characterization of their magnetic properties, with single-particle resolution and good statistics. Here, we report intra-pair magnetophoresis as a method to accurately quantify the field-dependent magnetic moments of magnetic particles and to rapidly generate histograms of the magnetic moments with good statistics. We demonstrate our method with particles of different sizes and from different sources, with a measurement precision of a few percent. We expect that intra-pair magnetophoresis will be a powerful tool for the characterization and improvement of particles for the upcoming field of particle-based nanobiotechnology.

• 出版日期2013-7-22