摘要
An efficient and eco-friendly synthesis of 1-oxo-hexahydroxanthenes has been expediently accomplished by a reaction of salicylaldehyde with cyclohexane-1,3-dione or dimedone in water as universal solvent at reflux condition without a catalyst. Excellent yields of the products, operational simplicity, simple work-up and catalyst-free synthesis are attractive features of this green protocol.
- 出版日期2010-12