Fetal and neonatal complications related to prolonged pregnancy

作者：Chantry A A; Lopez E^*

来源：Journal de Gynecologie Obstetrique et Biologie de la Reproduction, 2011, 40(8): 717-725.

DOI：10.1016/j.jgyn.2011.09.007

• Prolonged pregnancy
• Post-term
• Large for gestational age
• Perinatal asphyxia
• Meconium aspiration syndrome

Objective. - To evaluate fetal and neonatal outcomes related to prolonged pregnancy.
Methods. - This study is based on Pubmed search, Cochrane library and HAS recommendations.
Results. - The risk of fetal complications including macrosomia (6%), oligohydramnios (10 %-15 %), abnormal fetal heart rate pattern and meconium-stained fluid is increased in prolonged pregnancy (>= 41(+0) weeks). The rate of stillbirth was estimated between 1.6%0 and 3.0%0 live births according to countries in post-term pregnancies (>= 42(+0) weeks). The risk of umbilical cord pH less than 7.10, Apgar score at five minutes inferior to 7, ICU admissions and perinatal asphyxia is increased in post-term infants (>= 42(+0) weeks) compared with term infants. The risk of neurologic ccimplications including neonatal convulsion, hypoxic ischemic encephalopathy, cerebral palsy, developmental deviations and epilepsy in childhood is increased in post-term infants. The risk of meconium aspiration syndrome, neonatal sepsis, and birth trauma including shoulder dystocia and bone fracture is increased in post-term infants. The rate of perinatal mortality increases in post-term infants. The perinatal mortality in post-term infants could be explained by perinatal asphyxia and meconium aspiration syndrome.
Conclusions. - The risk of perinatal complications and mortality are increased in prolonged pregnancy.

• 出版日期2011-12