Aligned PVDF-TrFE Nanofibers With High-Density PVDF Nanofibers and PVDF Core-Shell Structures for Endovascular Pressure Sensing

作者：Sharma Tushar^*; Naik Sahil; Langevine Jewel; Gill Brijesh; Zhang John X J

来源：IEEE Transactions on Biomedical Engineering, 2015, 62(1): 188-195.

DOI：10.1109/TBME.2014.2344052

• Terms Core shell
• catheter
• nanofibers
• polyvinyledenedifluoride-tetrafluoroethylene (PVDF-TrFE)
• pressure sensor

Nanostructures of polyvinyledenedifluoridetetrafluoroethylene (PVDF-TrFE), a semicrystalline polymer with high piezoelectricity, results in significant enhancement of crystallinity and better device performance as sensors, actuators, and energy harvesters. Using electrospinning of PVDF to manufacture nanofibers, we demonstrate a new method to pattern high-density, highly aligned nanofibers. To further boost the charge transfer from such a bundle of nanofibers, we fabricated novel core-shell structures. Finally, we developed pressure sensors utilizing these fiber structures for endovascular applications. The sensors were tested in vitro under simulated physiological conditions. We observed significant improvements using core-shell electrospun fibers (4.5 times gain in signal intensity, 4000 mu V/mmHg sensitivity) over PVDF nanofibers (280 aeV/mmHg). The preliminary results showed that core-shell fiber-based devices exhibit nearly 40-fold higher sensitivity,

• 出版日期2015-1