A Tale of Two Elabela Null Mice

作者:Papangeli Irinna; Chun Hyung J*
来源:Trends in Endocrinology and Metabolism, 2017, 28(11): 756-757.
DOI:10.1016/j.tem.2017.09.004

摘要

Elabela (ELA), the second peptide ligand for the apelin receptor, APLNR, was previously found in lower vertebrates to be crucial for endoderm and cardiac development. Two new studies report on the phenotypes of Ela null mice, ranging from defective embryogenesis to preeclampsia, providing new insights and raising greater intrigue on this cardiometabolic pathway.

  • 出版日期2017-11