Microwave Solid Phase Synthesis, Characterization and Antimicrobial Activities of Mononuclear Cobalt(II) Complex with 4-Chloro-benzoic acid 4-[3(4-chloro-phenyl)-3-hydroxy-acryloyl]-3-hydroxy-phenyl ester

作者：Xu, Suo-Ping^*; Li, Tuan-Jie; Xu, Guo; Pei, Yuan

来源：Asian Journal of Chemistry, 2013, 25(11): 6105-6108.

DOI：10.14233/ajchem.2013.14269

• Microwave solid phase synthesis
• beta-Diketone ligand
• Mononuclear cobalt(II) complex
• Antibacterial activity

One mononuclear complex has been designed and synthesized by a beta-diketone ligand 4-chloro-benzoic acid 4-[3-(4-chloro-phenyl)-3-hydroxy-acryloyl]-3-hydroxy-phenyl ester (L) with CoCl2 center dot 6H(2)O in microwave radiation assistance. The complex was characterized by X-ray crystallography, confirming that the central cobalt(II) was coordinated by four oxygens from two beta-diketone ligand and two oxygens from two ethanols. The complex was assayed for in vitro antibacterial (B. subtilis, S. aureus, S. faecalis, P. aeruginosa, E. coli and E. cloacae) activities and showed better antimicrobial activity against Gram positive strains than Gram negative strains.

• 出版日期2013-9
• 单位中国矿业大学（北京）