Age at menarche and indigenous ancestry. A population study in Chile

作者：Ossa Ximena^*; Bustos Patricia; Munoz Sergio; Amigo Hugo

来源：Revista Medica de Chile, 2012, 140(8): 1035-1042.

DOI：10.4067/S0034-98872012000800010

• Factors
• Groups
• Menarche
• Socioeconomic factors

Background: The age at menarche may influence decisively health and disease in women. It also indicates the beginning of the reproductive period and, as a consequence, the possibility of biological continuity for the human species. Genetic and environmental determinants define the age of menarche and can explain differences found among different populations. Aim: To determine the age at menarche among adolescents with different levels of indigenous descent (parental indigenous surnames), considering the effect of socioeconomic and demographic factors. Material and Methods: An observational study of historic cohorts of 8.624 girls from the Araucania Region (central-southern Chile) was carried out. Data were collected by health professionals using a previously validated questionnaire. Occurrence of menarche was estimated through survival analysis and compared between groups (according to indigenous parental surnames) adjusted for parents%26apos; income and educational level and provenance (rural/urban). Results: Estimated median age of menarche was 151 months (95% CI: 150-151). In female with four indigenous surnames, menarche occurred two months later than girls without indigenous surnames and with two indigenous surnames (p %26lt; 0,001). In girls whose parents had lowest level of schooling, the difference increased to eight months later (p %26lt; 0,005). Conclusions: Age at menarche in the group with higher indigenous descent is later even if socio-economic conditions remain stable. Genetic factors might play an important role, however conditions of vulnerability can influence and further delay the onset of reproductive competency (Rev Med Chile 2012; 140: 1035-1042).

• 出版日期2012-8