A macrocyclic F-19-MR based probe for Mn2+ sensing

作者：Sarkar Anindita; Biton Inbal E; Neeman Michal; Datta Ankona^*

来源：Inorganic Chemistry Communications, 2017, 78: 21-24.

DOI：10.1016/j.inoche.2017.02.008

• Manganese sensor
• F-19-MR probe
• Fluorinated aza-macrocycle
• F-19 relaxation enhancement

We report a novel fluorinated aza-macrocycle that affords a linear increase in longitudinal and transverse F-19 NMR relaxation rates between 100 mu M to 1 mM Mn2+ concentrations. The linear response which is unaffected in the presence of other biologically relevant metal ions and F-19-MR phantom images of macrocycle solutions in presence of Mn2+ indicate the potential applicability of the probe as a F-19-MR based Mn2+ sensor.

• 出版日期2017-4