Adherence of probiotic bacteria to human colon epithelial cells and inhibitory effect against enteric pathogens - In vitro study

作者：Adriana Nowak^*; Ilona Motyl; Katarzyna Slizewska; Zdzislawa Libudzisz; Elzbieta Klewicka

来源：International Journal of Dairy Technology, 2016, 69(4): 532-539.

DOI：10.1111/1471-0307.12286

• Intestinal microbiota
• Competition
• Diarrhoea
• Pathogens
• Caco-2 cells

The aim of this study was to determine the anti-adherence properties of three probiotic lactobacillus strains (Lb. rhamnosus 0900, Lb. rhamnosus 0908 and Lb. casei 0919), and their mixture against pathogens: Escherichia coli ATCC 10536, Salmonella enterica serovar Typhimurium ATCC 14028 and Candida albicans ATCC 10231 using Caco-2 human colon adenocarcinoma cells. All strains of lactobacilli and the probiotic mixture to the greatest extent inhibited adherence of S. Typhimurium, up to 91%. Lb. rhamnosus 0900 inhibited E. coli by 75.9%, and Lb. casei 0919 decreased adherence of C. albicans by 49%. All pathogens activated the adherence of the mixture of probiotic bacteria.

• 出版日期2016-11