Autophagy-disrupted LC3 abundance leads to death of supporting cells of human oocytes

作者：Woojin Kang; Eri Ishida; Kenji Yamatoya; Akihiro Nakamura; Mami Miyado; Yoshitaka Miyamoto; Maki Iwai; Kuniko Tatsumi; Takakazu Saito; Kazuki Saito; Natsuko Kawano; Toshio Hamatani; Akihiro Umezawa; Kenji Miyado; Hidekazu Saito

来源：Biochemistry and Biophysics Reports, 2018, 15: 107-114.

DOI：10.1016/j.bbrep.2018.08.002

• Human granulosa cells
• Autophagy
• LC3
• ATG7
• Cell death
• Cumulus cells

Abstract(#br)Autophagic recycling of cell parts is generally termed as the opposite of cell death. Here, we explored the relation between cell death and autophagy by examining granulosa cell layers that control oocyte quality, which is important for the success of fertilization. Granulosa cell layer...

• 出版日期2018