ANTIPROLIFERATIVE ACTIVITY OF CYANO-SUBSTITUTED PYRANS AND 1,2,5,6,7,8-HEXAHYDROQUINOLINE-3,3,4,4-TETRACARBONITRILES

作者：Mar'yasov M A; Sheverdov V P^*; Davydova V V; Nasakin O E

来源：Pharmaceutical Chemistry Journal, 2017, 50(12): 798-799.

DOI：10.1007/s11094-017-1534-2

• methyl-6-amino-3-acyl-4-aryl-5-cyano-4H-pyran-2-carboxylates
• 9-aryl-12-imino-10,11-dioxatricyclo[5.3.2.0(1,6)]dodecane-7,8,8-tricarbo nitriles
• and 1,2,5,6,7,8-hexahydroquinoline-3,3,4,4-tetracarbonitriles
• tetracyanoethylene
• arylidenemalononitriles
• antiproliferative activity

The antiproliferative activity of methyl-6-amino-3-acyl-4-aryl-5-cyano-4H-pyran-2-carboxylates, 9-aryl-12-imino-10, 11-dioxatricyclo[5.3.2.0(1,6)]dodecane-7,8,8-tricarbonitriles, and 1,2,5,6,7,8-hexahydroquinoline3,3,4,4-tetracarbonitriles was investigated.

• 出版日期2017-3