A Plasmid Bearing the bla(CTX-M-15) Gene and Phage P1-Like Sequences from a Sequence Type 11 Klebsiella pneumoniae Isolate

作者：Shin Juyoun; Ko Kwan Soo^*

来源：Antimicrobial Agents and Chemotherapy, 2015, 59(10): 6608-6610.

DOI：10.1128/AAC.00265-15

Plasmid pKP12226 was extracted and analyzed from a CTX-M-15-producing Klebsiella pneumoniae sequence type 11 (ST11) isolate collected in South Korea. The plasmid represents chimeric characteristics consisting of a pIP1206-like backbone and lysogenized phage P1-like sequences. It bears a resistance region that includes resistance genes to several antibiotics and is different from previously characterized plasmids from South Korea bearing bla(CTX-M-15). It may have resulted from recombination between an Escherichia coli plasmid backbone, a bla(CTX-M-15)-bearing resistance region, and lysogenized phage P1-like sequences.

• 出版日期2015-10