Microtropins A-I: 6 '-O-(2 '' S,3 '' R)-2 ''-Ethyl-2 '',3 ''-dihydroxybutyrates of aliphatic alcohol beta-D-glucopyranosides from the branches of Microtropis japonica

作者：Uemura Yuka; Sugimoto Sachiko; Matsunami Katsuyoshi; Otsuka Hideaki^*; Takeda Yoshio; Kawahata Masatoshi; Yamaguchi Kentaro

来源：Phytochemistry, 2013, 87: 140-147.

DOI：10.1016/j.phytochem.2012.11.007

• Microtropis japonica
• Celastraceae
• Microtropin
• (2S,3R)-2-Ethyl-2,3-dihydroxybutyric acid
• 3-Hydroxy-2-methylbutanenitrile (E)-4-Hydroxy-2-(hydroxymethyl)but-2-enenitrile

From the branches of Microtropis japonica (Celastraceae), nine aliphatic glucosides, named microtropins A-I, were isolated. The 6-position of glucose was esterified with (2S,3R)-2-ethyl-2,3-dihydroxybutyric acid. Microtropins A-D contained a rare natured product nitrile functional group in their aglycones. The absolute structures of the (25,3R)-2-ethyl-2,3-dihydroxybutyric acid moiety and aglycone of microtropin A were determined by an X-ray crystallographic method.

• 出版日期2013-3