Multisystem reactions during egg oral food challenges may be associated with less severe reactions on initial presentation

作者：Vitalpur Girish^*; Esquivel Ann; Kloepfer Kirsten M; Slaven James E; Leickly Frederick E

来源：Allergy, Asthma and Clinical Immunology, 2016, 12(1): 21.

DOI：10.1186/s13223-016-0125-1

• Egg allergy
• Extensively heated (EH) egg allergy
• Oral food challenge (OFC)
• Reaction severity
• Type of reaction

In this study, we assessed whether multisystem reactions to egg and extensively-heated (EH) egg during OFCs were associated with a history of multisystem reactions. Records of children, who underwent OFC to egg or EH egg over a five-year period were reviewed. Of the 120 challenges, 26 (21.67 %) failed, with 38.4 % (10/26) having multisystem reactions. Of the 13 who had multisystem reactions on initial presentation, only two (15.4 %) had a similar OFC outcome. Eighty percent (8/10) of those who had a multisystem OFC reaction had a less severe initial presentation. Initial and OFC multisystem reactions were not associated with each other.

• 出版日期2016-4-28