MOTOR NERVE CONDUCTION STUDY IN CAUDA EQUINA WITH HIGH-VOLTAGE ELECTRICAL STIMULATION IN MULTIFOCAL MOTOR NEUROPATHY AND AMYOTROPHIC LATERAL SCLEROSIS

作者：Akaza Miho; Kanouchi Tadashi; Inaba Akira; Numasawa Yoshiyuki; Irioka Takashi; Mizusawa Hidehiro; Yokota Takanori^*

来源：Muscle & Nerve, 2011, 43(2): 274-282.

DOI：10.1002/mus.21855

• amyotrophic lateral sclerosis
• cauda equina
• high-voltage electrical stimulation
• multifocal motor neuropathy
• multifocal motor neuropathy without conduction block

In this study we aim to establish a motor nerve conduction study (NCS) for the cauda equina and examine its usefulness in multifocal motor neuropathy (MMN) and amyotrophic lateral sclerosis (ALS). NCS of the tibial nerve proximal to the knee was performed with an optimized high-voltage electrical stimulation (HV-ES) method in 21 normal subjects, 5 with MMN, and 11 with ALS. HV-ES, but not magnetic stimulation, could supramaximally stimulate the cauda equina. Cauda equina motor conduction time determined by HV-ES, but not that with F-waves, correlated well with cauda equina length on magnetic resonance imaging. HV-ES revealed proximal lesions in 4 MMN patients but in none of the ALS patients. Importantly, 1 patient with 'MMN without conduction block (CB)' had a CB in the cauda equina. Cauda equina motor conduction is better evaluated by HV-ES than with F-wave study or magnetic stimulation. HV-ES can help to distinguish MMN and 'MMN without CB' from ALS. Muscle Nerve 43: 274-282, 2011

• 出版日期2011-2