Modeling techniques of multidimensional quantitative structure-activity relationship in computer-aided drug design

作者：Liang GZ^*; Mei H; Zhou Y; Li ZL

来源：Progress in Chemistry, 2006, 18(1): 120-127.

• multidimensional quantitative structure-activity relationship (MD QSAR)
• computer-aided drug design(CADD)
• molecular modeling and optimization

Multidimensional quantitative structure-activity relationship (MD QSAR) has been successfully applied as a crucial technique for computer-aided drug design (CADD) in various fields. Based on plentiful literatures, different strategies and various ';methodologies of MD QSAR are systematically summarized by combining with research works in authors'; laboratory. Recent progress of MD QSAR in CADD is reviewed.

• 出版日期2006-1
• 单位重庆大学