Addition of Diazo Compounds ipso-C-H Bond to Carbon Disulfide: Synthesis of 1,2,3-Thiadiazoles under Mild Conditions

作者：Zhang, Lei; Sun, Beiqi; Liu, Qianyi; Mo, Fanyang^*

来源：Journal of Organic Chemistry, 2018, 83(7): 4275-4278.

DOI：10.1021/acs.joc.8b00383

• SYSTEMIC ACQUIRED-RESISTANCE
• ALPHA-ENOLICDITHIOESTERS
• BIOLOGICAL-ACTIVITY
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We describe here an operationally simple and straightforward synthesis method for a series of diverse 4,5-disubstituted 1,2,3-thiadiazoles via the nucleophilic addition of a-diazo carbonyl compounds to carbon disulfide. This method features using abundant and inexpensive carbon disulfide under mild reaction conditions.

• 出版日期2018-4-6
• 单位北京大学