Modifier genes of hereditary hearing loss

作者:Friedman T*; Battey J; Kachar B; Riazuddin S; Noben Trauth K; Griffith A; Wilcox E
来源:Current Opinion in Neurobiology, 2000, 10(4): 487-493.
DOI:10.1016/S0959-4388(00)00120-3

摘要

Phenotypic variation between individuals with the same disease alleles may be attributable to the genotype at another locus, which is referred to as a modifier gene. Recent functional studies of modifier genes of hearing-loss loci have begun to refine our understanding of hearing processes and will guide the rational design of medical therapies for hearing loss.

  • 出版日期2000-8