Association of the expression levels in the longissimus muscle and a SNP in the CDC10 gene with marbling in Japanese Black beef cattle

作者：Tong, B.; Gao, G. Q.; Muramatsu, Y.; Ohta, T.; Kose, H.; Li, G. P.; Fatchiyah, F.; Yamada, T.^*

来源：Meat Science, 2015, 108: 28-31.

DOI：10.1016/j.meatsci.2015.05.017

• Association
• Beef cattle
• CDC10
• Expression
• Marbling
• Single nucleotide polymorphism

The septin 7 (CDC10) gene, involved in cellular proliferation, has been previously shown to be expressed at different levels in the longissimus muscle (LM) between low-marbled and high-marbled steer groups by differential-display PCR. It is located within the genomic region of a quantitative trait locus for marbling, and thus was considered as a positional functional candidate gene for marbling. In this study, we showed that the CDC10 expression levels in the LM were positively correlated with marbling in Japanese Black (JB) steers (P < 0.0001). Further, an association analysis indicated that a SNP in the promoter region of the CDC10 gene was associated with marbling using 99 JB sires (P = 0.03) and 542 JB paternal half-sib progeny steers from a sire homozygous for G allele at the SNP (P < 0.0001). These findings suggest possible effects of the expression levels in the LM and the SNP of the CDC10 gene on marbling in JB cattle.

• 出版日期2015-10
• 单位内蒙古大学