摘要
The MeOH extract from the flowers of Bellis perennis was found to show pancreatic-lipase inhibitory activity (IC(50) 455 mu g/ml). From the extract, seven new triterpene saponins named perennisaponins 0 (1; IC(50) 163 mu M), H (2; 137 mu M), 1(3: 147 mu M), J (4; 148 mu M), K (5; 223 mu M), L (6; 81.4 mu M), and M (7; 195 mu M) were isolated as pancreatic lipase inhibitors. The stereostructures of 1-7 were elucidated on the basis of chemical and spectroscopic evidence.
- 出版日期2010