A Tale of Division and Polarization in the Mammalian Embryo

作者:Srinivas Shankar*; Rodriguez Tristan Argeo*
来源:Developmental Cell, 2017, 40(3): 215-216.
DOI:10.1016/j.devcel.2017.01.008

摘要

The first cell fate choice in mouse development is the segregation of the embryonic inner cell mass and the extra-embryonic trophectoderm. In this issue of Developmental Cell, Korotkevic and colleagues (2017) show that the interplay between cell polarization and cell-cell contact drives the segregation of these lineages, providing a framework for self-organization in development.

  • 出版日期2017-2-6

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