A one-pot [Bmim]OH-mediated synthesis of 3-benzamidocoumarins

作者：Yadav Lal Dhar S^*; Singh Santosh; Rai Vijai K

来源：Tetrahedron Letters, 2009, 50(19): 2208-2212.

DOI：10.1016/j.tetlet.2009.02.166

• Ionic-liquids
• 3-Aminocoumarins
• Benzopyrans
• Atom-efficient
• Salicylaldehydes
• 2-Phenyl-1,3-oxazolan-5-one

The first example of an ionic liquid-promoted one-pot synthesis of 3-benzamidocoumarins from salicylaldehydes and 2-pheny-1,3-oxazolan-5-one via Knoevenagel condensation-ring transformation cascades has been reported. No by-product formation, operational simplicity, ambient temperature and high yield (85-97%) are the salient features of the present synthetic protocol. After isolation of the product, the ionic liquid, [Bmim]OH can be easily recycled for further use without any loss of efficiency.

• 出版日期2009-5-13