A rare case of a pineoblastoma with a rhabdomyoblastic component

作者：Homma Taku^*; Hemmi Akihiro; Ohta Takashi; Kusumi Yoshiaki; Yoshino Atsuo; Hao Hiroyuki

来源：Neuropathology, 2017, 37(3): 227-232.

DOI：10.1111/neup.12346

• medullomyoblastoma
• pineal anlage tumor
• pineal gland
• pineoblastoma
• rhabdomyoblastic component

Pineal anlage tumor (PAT) is a rare subtype of pineoblastoma (PB), which shows a poor prognosis. We report a case of a 5-year-old boy with PB with a rhabdomyoblastic component. He presented at a local clinic with vomiting and was transferred to our hospital following discovery of a pineal mass. An endoscopic biopsy was performed and was diagnosed as a PB with a rhabdomyoblastic component. Histopathology of PAT is characterized by both neuroectodermal and ectomesenchymal differentiation, and only a few confirmed cases have been reported. Although the histopathological features of the reported case resembled that of PAT, the ectomesenchymal component in the presented case was only a rhabdomyoblastic one. Therefore, we have diagnosed this case as PB with a rhabdomyoblastic component. As PAT is a rare pineal tumor, clinical, histopathological and genetic evaluation of additional cases is needed to define the characteristics of PAT as one of the pineal gland tumors.

• 出版日期2017-6