An integrated approach to correction for off-resonance effects and subject movement in diffusion MR imaging

作者：Andersson, Jesper L. R.^*; Sotiropoulos, Stamatios N.

来源：NeuroImage, 2016, 125: 1063-1078.

DOI：10.1016/j.neuroimage.2015.10.019

• Diffusion
• Eddy current
• Movement
• Susceptibility
• Registration

In this paper we describe a method for retrospective estimation and correction of eddy current (EC)-induced distortions and subject movement in diffusion imaging. In addition a susceptibility-induced field can be supplied and will be incorporated into the calculations in a way that accurately reflects that the two fields (susceptibility- and EC-induced) behave differently in the presence of subject movement. The method is based on registering the individual volumes to a model free prediction of what each volume should look like, thereby enabling its use on high b-value data where the contrast is vastly different in different volumes. In addition we show that the linear EC-model commonly used is insufficient for the data used in the present paper (high spatial and angular resolution data acquired with Stejskal-Tanner gradients on a 3 T Siemens Verio, a 3 T Siemens Connectome Skyra or a 7 T Siemens Magnetome scanner) and that a higher order model performs significantly better. The method is already in extensive practical use and is used by four major projects (the WU-UMinn HCP, the MGH HCP, the UK Biobank and theWhitehall studies) to correct for distortions and subject movement.

• 出版日期2016-1-15