Antibiotic Resistance of Campylobacter jejuni and C. coli Isolated from Children with Diarrhea in Thailand and Japan

作者：Ngan Thi Kim Pham; Thongprachum Aksara; Dinh Nguyen Tran; Nishimura Shuichi; Shimizu Onda Yuko; Quang Duy Trinh; Khamrin Pattara; Ukarapol Nuthapong; Kongsricharoern Tipachan; Komine Aizawa Shihoko; Okitsu Shoko; Maneekarn Niwat; Hayakawa Satoshi; Ushijima Hiroshi

来源：Japanese Journal of Infectious Diseases, 2016, 69(1): 77-79.

DOI：10.7883/yoken.JJID.2014.582

A total of 29 Campylobacter jejuni and C. coli strains were isolated from Thai and Japanese children with diarrhea using the Loop-mediated Isothermal Amplification method. The samples were evaluated for mutations in gyrA and 23S rRNA in order to assess resistance against fluoroquinolones and macrolides, respectively. Among the isolated strains, 9 (8 C. jejuni and 1 C. colt) were from Thai children, and the other 20 (C. jejuna) were isolated from Japanese children. High fluoroquinolone resistance rates were observed in Thai (66.7%) and Japanese (90%) children. Macrolide resistance was not observed in Japanese children but was observed at a considerable rate of 12.5% of C. jejuni isolated in the Thai cohort. The results indicate that continuous monitoring of resistance of Campylobacter strains to fluoroquinolones and macrolides is definitely necessary.

• 出版日期2016-1