A Layered Model for the Growth of Solid Tumors in Vascular Phase

作者：Zhan Kuihua^*; Bai Lun; Dai Hongqin

来源：6th China-Japan International Conference on Mechatronics (CJCM 2010), 2010-09-10 to 2010-09-12.

DOI：10.4028/www.scientific.net/AMM.43.736

• Solid tumor
• Layered model
• Vascular phase
• Angiogenesis

We divide a solid tumor in vascular phase into a vascular layer, an oxygen-diffusion layer, an oxygen-resistant layer and a necrotic layer outside-to-inside, and have constructed a layered model for tumor growth. The actual growth curves of the tumors have been obtained by using different invasion speeds of the vascular layer. The simulative calculation results indicate that the angiogenesis rate is positively correlated with malignant degree of the tumors, if the tumors enter vascular phase, survival time of tumor patients is about 1-4 years, but the tumor patients without angiogenesis can live with tumor.

• 出版日期2011
• 单位苏州大学