科研之友
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摘要
Objective: To study upper airway breathing in 115 children annually from 8 to 17 years of age with the hypothesis that upper airway respiratory needs increase steadily during growth and show sexual dimorphism. Material and Methods: To calculate nasal resistance, airflow rate (mL/s) and oronasal pressures (cmH(2)O) were measured during rest breathing in a seated position using the pressure-flow technique. Results: Median values of oronasal pressure ranged at different ages in girls from 0.88 to 1.13 and in boys from 0.92 to 1.44 cmH(2)O, being 0.95 and 0.93 cmH(2)O at the age of 17 years, respectively. The gender differences were statistically significant in four age groups (P < .05 by the Mann-Whitney test). Mean values of nasal resistance decreased from 8 to 17 years of age in girls from 4.0 (63.27) to 2.4 (62.30) and in boys from 3.3 (62.48) to 1.5 (60.81) cmH(2)O/L/s. However, there was an increase in resistance in 11-year-old girls and 12-year-old boys and at the age of 15 in both genders (P < .05 by paired t-test). Conclusions: Respiratory efforts stabilize oronasal pressure to maintain vital functions at optimal level. Nasal resistance decreased with age but increased temporarily at the prepubertal and pubertal phases, in accordance with other growth and possibly hormonal changes. When measuring upper airway function for clinical purposes, especially in patients with sleep apnea, asthma, allergies, cleft palate, or maxillary expansion, the measurements need to be compared with age-and genderspecific values obtained from healthy children.
- 出版日期2016-7
