科研之友
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摘要
A concise and straightforward synthesis of two amino-DNJ derivatives, 6-amino-6-deoxy-DNJ and 6-amino-1,6-dideoxy-L-talonojirimycin is described from a commercial and cheap starting material. The methodology employed takes advantage of dia-stereoselective reductive amination to achieve the two non-natural iminosugars in three and five steps, respectively.
- 出版日期2010-6
