Detection of aac(6 %26apos;)-Ib-cr in Avian Pathogenic Escherichia coli Isolates in Japan

作者：Kawanishi Michiko^*; Ozawa Manao; Hiki Mototaka; Abo Hitoshi; Kojima Akemi; Asai Tetsuo

来源：Journal of Veterinary Medical Science, 2013, 75(11): 1539-1542.

DOI：10.1292/jvms.13-0185

• aac(6 %26apos
• )-Ib-cr
• APEC
• PMQR
• quinolone resistance

We investigated the prevalence of plasmid-mediated quinolone resistance (PMQR) genes in avian pathogenic Escherichia coli (APEC) strains in Japan. A total of 117 APEC strains collected between 2004 and 2007 were examined for PMQR genes (qnrA, qnrB, qnrC, qnrD, qnrS, aac(6 %26apos;)-Ib-cr, qepA and oqxAB) by polymerase chain reaction. None of the APEC strains carried qnrA, qnrB, qnrC, qnrD, qnrS, qepA or oqxAB, but one of the isolates was identified as an AAC (6%26apos;)-Ib-cr producer. Phylogenetic grouping, multi-locus sequence typing and serotyping showed that this isolate belonged to phylogenetic group A, sequence type 167 and untypable serogroup. To our knowledge, this is the first report of the aac (6%26apos;)-Ib-cr gene in bacteria from food-producing animals in Japan.

• 出版日期2013-11