A convenient synthesis of (E)-conjugated polyene sulfonyl derivatives with excellent stereospecificity

作者：Yu, Chunyan; Lv, Zhongwen; Xu, Sheng^*; Zhang, Jun

来源：Tetrahedron Letters, 2018, 59(34): 3234-3237.

DOI：10.1016/j.tetlet.2018.05.060

• Dihaloalkane
• Disulfonyl chloride
• Elimination
• Polyene sulfonyl derivatives

A highly selective synthesis of conjugated polyene sulfonyl derivatives is described via the elimination of disulfonyl chloride with readily accessible raw material dihaloalkane. The protocol offers a convenient way to form sulfonamides, sulfonates and even sulfones. Furthermore, this method was manipulated under mild condition with simple operation in high yield to afford only trans products.

• 出版日期2018-8-22
• 单位华东理工大学