An IVUS image-based approach for improvement of coronary plaque characterization

作者：Taki Arash^*; Roodaki Alireza; Setarehdan Seyed Kamaledin; Avansari Sara; Unal Gozde; Navab Nassir

来源：Computers in Biology and Medicine, 2013, 43(4): 268-280.

DOI：10.1016/j.compbiomed.2012.12.008

• IVUS
• Plaque
• Characterization
• Virtual histology

Virtual Histology-Intravascular Ultrasound (VH-IVUS) is widely used for studying atherosclerosis plaque composition. However, one of the main limitations of the VH-IVUS relates to its dependence to the Electrocardiogram (ECG)-gated acquisition. To overcome this limitation, this paper proposes a robust image-based approach for characterization of the plaques using IVUS images. The proposed method consists of three main steps of (1) shadow detection: as an efficient preprocessing step to identify and remove acoustic shadow regions; (2) feature extraction: a combination of gray-scale based features and textural descriptors; and (3) classification: to classify each pixel into one of the three classes (calcium, necrotic core and fibro-fatty). In order to evaluate the efficiency of the proposed algorithm two in-vivo and ex-vivo data sets are considered. The kappa values of 0.639 on in-vivo and 0.628 on ex-vivo tests with VH-IVUS and the histology images labeled by the experts respectively indicate the effectiveness of the proposed algorithm.

• 出版日期2013-5-1