Detection of a sensitization to neuromuscular blocking agents at the time of the diagnosis of a pholcodine allergy

作者：Fourel M; Diot N; Dubost R; Garnier L; Bienvenu F; Piriou V; Bienvenu J; Rouzaire P^*

来源：Revue Francaise d Allergologie, 2012, 52(2): 97-100.

DOI：10.1016/j.reval.2011.11.003

• Pholcodine allergy
• Neuromuscular blocking agents (NMBA)
• Peranaesthetic accident
• Quaternary ammonium

Neuromuscular blocking agents (NMBA) are the molecules, the most commonly involved in anaphylactic peranaesthetic shocks. This case report concerns a 66-year-old atopic woman, presenting with NMBA sensitization detected at the time of the exploration of a pholcodine allergy. It is very likely that pholcodine is a cause of NMBA sensitization due to the structural homology between these molecules. Consequently, in a pholcodine allergic patient, a NMBA sensitization must be sought to reduce the risk of peranaesthetic anaphylactic accidents.

• 出版日期2012-3