Molecular characteristics of clinical methicillin-resistant Staphylococcus pseudintermedius harboring arginine catabolic mobile element (ACME) from dogs and cats

作者：Yang Ching; Wan Min Tao; Lauderdale Tsai Ling; Yeh Kuang Sheng; Chen Charles; Hsiao Yun Hsia; Chou Chin Cheng^*

来源：Veterinary Journal, 2017, 224: 46-49.

DOI：10.1016/j.tvjl.2017.06.002

• Animal
• Arginine catabolic mobile element
• Methicillin-resistant Staphylococcus pseudintermedius
• Multidrug-resistance

This study aimed to investigate the presence of arginine catabolic mobile element (ACME) and its associated molecular characteristics in methicillin-resistant Staphylococcus pseudintermedius (MRSP). Among the 72 S. pseudintermedius recovered from various infection sites of dogs and cats, 52 (72.2%) were MRSP. ACME-arcA was detected commonly (69.2%) in these MRSP isolates, and was more frequently detected in those from the skin than from other body sites (P= 0.047). There was a wide genetic diversity among the ACME-arcA-positive MRSP isolates, which comprised three SCCmec types (II-III and V) and 15 dru types with two predominant clusters (9a and 11a). Most MRSP isolates were multidrug-resistant. Since S. pseudintermedius could serve as a reservoir of ACME, further research on this putative virulence factor is recommended.

• 出版日期2017-7