An Efficient and Straightforward Method to New Organic Compounds: Homodrimane Sesquiterpenoids with Diazine Units

作者：Kuchkova Kaleria; Aricu Aculina; Barba Alic; Vlad Pavel; Shova Sergiu; Secara Elena; Ungur Nicon; Zbancioc Gheorghita; Mangalagiu Ionel I^*

来源：Synlett, 2013, (6): 697-700.

DOI：10.1055/s-0032-1318253

• homodrimane
• sesquiterpenoids
• diazine
• one-pot bisacylation
• bisacylamide

A comprehensive study of the synthesis and structure of new homodrimane sesquiterpenoids with diazine skeleton is presented. This is the first synthesis of homodrimane sesquiterpenoids with diazine skeleton. In the same time, an efficient way for the one-pot bisacylation of 2-aminopyrimidine is reported. The structure of the bisacylamide was proven unambiguously, including the single-crystal X-ray structure determination. A reliable explication and feasible reaction mechanisms for the obtained compounds are presented.

• 出版日期2013-4