Monitoring parasite diversity for malaria elimination in sub-Saharan Africa

作者：Ghansah Anita; Amenga Etego Lucas; Amambua Ngwa Alfred; Andagalu Ben; Apinjoh Tobias; Bouyou Akotet Marielle; Cornelius Victoria; Golassa Lemu; Andrianaranjaka Voahangy Hanitriniaina; Ishengoma Deus; Johnson Kimberly; Kamau Edwin; Maiga Ascofare Oumou; Mumba Dieudonne; Tindana Paulina; Tshefu Kitoto Antoinette; Randrianarivelojosia Milijaona; William Yavo; Kwiatkowski Dominic P; Djimde Abdoulaye A^*

来源：Science, 2014, 345(6202): 1297-1298.

DOI：10.1126/science.1259423

The African continent continues to bear the greatest burden of malaria and the greatest diversity of parasites, mosquito vectors, and human victims. The evolutionary plasticity of malaria parasites and their vectors is a major obstacle to eliminating the disease. Of current concern is the recently reported emergence of resistance to the front-line drug, artemisinin, in South-East Asia in Plasmodium falciparum, which calls for preemptive surveillance of the African parasite population for genetic markers of emerging drug resistance. Here we describe the Plasmodium Diversity Network Africa (PDNA), which has been established across 11 countries in sub-Saharan Africa to ensure that African scientists are enabled to work together and to play a key role in the global effort for tracking and responding to this public health threat.

• 出版日期2014-9-12
• 单位河北医科大学