Diagnosis and treatment of nonadjacent cryptococcal infections at the L1 and S1 vertebrae

作者：Lai, Qi; Liu, Yuan; Yu, Xionglong; Lv, Xin; Wang, Qiang; Zhou, Yibiao; Guo, Runsheng^*; Zhang, Bin^*

来源：Orthopade, 2017, 46(1): 85-89.

DOI：10.1007/s00132-016-3349-3

• OSTEOMYELITIS

Cryptococcal spine infections are rare infections that are easy to misdiagnose and difficult to cure. Therefore, we report the case of a 25-year-old man who presented with nonspecific spinal lesions at L1 and S1. The patient underwent surgical removal of the lesions, and specimens were submitted for microbial identification, which identified a cryptococcal infection that was susceptible to amphotericin B. The patient exhibited marked improvement after receiving intravenous amphotericin B and remained asymptomatic (no back pain, fever, or other symptoms) at the 3aEuro and 9aEuromonth follow-ups. Similar cases of cryptococcal spine infections are rare, and we believe that our diagnostic findings and treatment experience may help improve the management of this rare disease.

• 出版日期2017-1
• 单位南昌大学