摘要

The scientific and technical literature addressing the synthesis of anisotropic iron-oxide nanoparticles of various shapes (cubic, rod-like, clustered, etc.) sized from 10 to 100 nm and their application for diagnostic magnetic resonance imaging (MRI) of tissues and organs is analyzed. The analysis indicates that the nanoparticle shape, size, and surface chemistry affect considerably relaxation parameters T-1 and T-2. Thus, cubic iron-oxide nanoparticles had the greatest T-2 values. Furthermore, rod-like and octapodal nanoparticles also exhibit rather high T-2 values so that they can be used as contrast agents for diagnostic MRI.

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