A comparative study of caffeic acid and a novel caffeic acid conjugate SMND-309 on antioxidant properties in vitro

作者：Wang, Fang; Yang, Jianxiong^*

来源：LEBENSMITTEL-WISSENSCHAFT UND-TECHNOLOGIE-FOOD SCIENCE AND TECHNOLOGY, 2012, 46(1): 239-244.

DOI：10.1016/j.lwt.2011.09.025

• Antioxidants
• Caffeic acid
• SMND-309
• Radical scavenging activity
• In vitro

Caffeic acid (3,4-dihydroxycinnamic acid, CA) has been identified as an important source of natural antioxidants in various agricultural products. SMND-309, which is a degradation product of salvianolic acid B, is a novel conjugate of CA, but little information has been known about its antioxidant activities. In present study, we compared in vitro antioxidant activities of CA and SMND-309 using different assays such as DPPH radical scavenging assay, hydroxyl radical scavenging assay, superoxide radical scavenging assay, total antioxidant activity, reducing power, and lipid peroxidation assay. Butylated hydroxytoluene (BHT) and Vitamin C (Vc) were used as the standard antioxidants. At the concentration of 20 mu g/ml, SMND-309 and CA exhibited 93.4% and 92.1% scavenging on DPPH radical, while BHT and Vc indicated an scavenging of 37.9% and 93.0% at the same concentration, respectively. Furthermore, SMND-309 is more effective on total antioxidant activity and hydroxyl radical scavenging than CA.

• 出版日期2012-4
• 单位陕西师范大学