Phenyliodine(III) Bis(trifluoroacetate) (PIFA)-Mediated Synthesis of Aryl Sulfides in Water

作者：Feng, Qingyuan; Chen, Dengfeng; Hong, Mei; Wang, Fei; Huang, Shenlin^*

来源：Journal of Organic Chemistry, 2018, 83(14): 7553-7558.

DOI：10.1021/acs.joc.8b00435

• C-H BOND
• CATALYZED REGIOSELECTIVE SULFENYLATION
• CARBON-SULFUR
• EFFICIENT SYNTHESIS
• CROSS-COUPLINGS
• PHENOL ETHERS
• INDOLES
• ACTIVATION
• THIOLATION
• ARENES

An environmentally benign method for the synthesis of aryl sulfides in water under mild conditions has been realized, in which arenes are coupled with equal stoichiometry of allyl sulfides. This arylthiolation is enabled by the presence of the Lipshutz surfactant, TPGS-750-M, using water as the recyclable reaction medium.

• 出版日期2018-7-20
• 单位南京林业大学