A 2.8 mm diameter scanhead for multispectral photoacoustic microscopy and optical coherence tomography

作者：Guo, Zhendong; Wang, Jie; Li, Zhongfei; Hu, Yang; Wu, Jigang^*; Chen, Sung-Liang^*

来源：Conference on Photons Plus Ultrasound - Imaging and Sensing, 2018-01-28 To 2018-02-01.

DOI：10.1117/12.2288967

• Photoacoustic imaging
• optical coherence tomography
• endoscopy
• photoacoustic microscopy
• multispectral
• high resolution

An endoscopic probe with high resolution and multiple contrasts provides useful diagnostic information. For example, a miniature probe capable of multimodal imaging including photoacoustic imaging, optical coherence tomography (OCT), and ultrasound has been reported. However, microscale resolution is only realized in OCT modality in the probe, which may restrict the applications where high resolutions for multiple contrasts are required. Here, we present an approach to construct a miniature scanhead with 2.8 mm in diameter that achieves high-resolution multispectral photoacoustic microscopy (PAM) and OCT. The method realizes high resolution of similar to 10 mu m for both PAM and OCT. We experimentally demonstrate ex vivo and in vivo imaging using the scanhead.

• 出版日期2018
• 单位上海交通大学; 区域光纤通信网与新型光纤通信系统国家重点实验室