Two-year clinical outcomes of patients with the second-generation cobalt-chromium sirolimus-eluting stents from the real-world FOCUS registry

作者：Zhang, Feng; Ge, Junbo^*; Qian, Juying; Ge, Lei; Zhou, Jun

来源：International Journal of Cardiology, 2013, 166(3): 750-752.

DOI：10.1016/j.ijcard.2012.09.172

• Sirolimus-eluting stent
• Percutaneous coronary intervention
• Coronary artery disease
• Cobalt-chromium alloy

The advent of drug-eluting stents (DES) has revolutionized the field of interventional cardiology and witnessed dramatic restenotic advantages over prior bare-metal stents (BMS) [1,2]. In the first generation DESs, stainless steel was widely used as the stent platform. Recently, several second-generation DESs have been developed by using cobalt-chromium stent platforms to further facilitate the procedure and improve the long-term DES safety [3]. As compared to the stainless steel, cobalt-chromium is stronger and more radio-opaque, therefore allowing to reduce the strut thickness while maintaining radial strength and to make the stent platforms more flexible and deliverable [4,5]. The FOCUS registry was a large-scale, prospective, nonrandomized, observational, multi-center, web-based program, designed to evaluate the safety and efficacy of a second-generation cobalt-chromium sirolimus-eluting stent (CoCr-SES) in routine treatment of patients with coronary artery diseases (CAD) [6,7]. The present report described the 2-year clinical outcomes of unrestricted use of CoCr-SES in patients from the FOCUS registry.

• 出版日期2013-7-1
• 单位复旦大学