Systemic Sarcoidosis with Thyroid Involvement

作者：Okuma Hideyuki; Hashimoto Koshi^*; Wang Xin; Ohkiba Noriaki; Murooka Nozomi; Akizuki Norikazu; Inazawa Takeshi; Ogawa Yoshihiro

来源：Internal Medicine, 2017, 56(16): 2181-2186.

DOI：10.2169/internalmedicine.8324-16

• thyroid sarcoidosis
• thyroid needle biopsy

A 66-year-old woman, who was diagnosed with iritis, visited our hospital due to general malaise. A blood analysis revealed hypercalcemia. Computed tomography revealed mediastinal and hilar lymph node hyperplasia. Moreover, (67)Gallium scintigraphy demonstrated strong accumulation in the lesions, suggesting sarcoidosis. A core needle biopsy (CNB) of the hypoechoic areas of the thyroid was performed because the patient refused to undergo a bronchoscopic examination. The scattering of slightly acidophilic epithelioid cell granulomas was observed in the pathological examination of the biopsy specimen. Based on this finding, the patient was diagnosed with sarcoidosis. Although sarcoidosis rarely involves the thyroid gland, in the present case, thyroid CNB was an alternative diagnostic method that allowed a pathological diagnosis to be obtained.

• 出版日期2017