Duloxetine hydrochloride

作者:Bhadbhade Mohan*; Hook James; Marjo Chris; Rich Anne; Lin Qinghong
来源:Acta Crystallographica Section E-Structure Reports Online, 2009, 65(9): O2294-U3259.
DOI:10.1107/S1600536809033996

摘要

The title compound [systematic name: N-methyl-3-( 1-naphthyloxy)-3-(2-thienyl) propan-1-aminium chloride], C18H20NOS center dot Cl-, was crystallized from 1,4-dioxane. Twofold rotational disorder exhibited by the thiophene ring in a 0.580 (5): 0.420 (5) ratio represents two different conformations of the molecule that exist in the same crystal form. The crystal structure contains strong N-H center dot center dot center dot Cl hydrogen bonds.

  • 出版日期2009-9